Charitable Trust—Termination by Judicial Decree

P, as administrator of settlor\u27s estate, brought an action to terminate a trust. Trial court dismissed the action. Held: Reversed. The failure of the trustees to administer the trust according to the provisions of the will and the failure to meet the deadline set by the court in a prior hearing of the same case justified termination of the trust. McLaren v. Schalkenbach Home for Boys, 141 Wash. Dec. 111, 206 P. 2d 345 (1952)

Selected Personality Constructs as Correlates of Personnel Appointment, Appraisal, and Mobility in Seventh-day Adventist Schools

Problem. Despite tentative postulations and explorations of the person/job interaction, the specific relationships between personality and occupational behavior are not clearly understood. In particular, the relationships between human temperament and various aspects of personnel administration in an educational setting are generally unknown. The purpose of this study was to profile the temperament traits of professional educators in the Seventh-day Adventist school system, grouped on the basis of occupationally relevant selection variables; and to investigate the role of personality as it relates to personnel appointment, appraisal, and mobility. Method. A demographic questionnaire and the Temperament Inventory were administered to 486 teachers, teacher/principals, principals, supervisors, and superintendents in nine local conference school systems of the Seventh-day Adventist Church. Phlegmatic, sanguine, choleric, and melancholy traits were profiled for selected subgroups and statistically compared using Cattell\u27s Coefficient of Pattern Similarity. Significant correlations were subjected to graphic comparisons as well. Results. Significant similarities and/or dissimilarities in personality emerged when profiles were contrasted on the bases of sex, professional position, perceived recruiter, preferred school size, rated competence, advancement status, and records of job stability. No significant results were observed when profiles were compared on the bases of geographic region, years of experience, assigned grade levels, assigned school size, and administrator/employee similarity. Conclusions. Analyses of the data prompted eighteen conclusions relative to the purpose for which the study was conducted. Each was generalized only to the population described for the study (i.e., K-10 Seventh-day Adventist educators of non-black conferences in North America). (1) Adventist educators collectively exhibit a choleric/phlegmatic personality. (2) Male and female educators collectively differ in personality. (3) The population is geographically and experientially heterogenous. (4) The population is highly mobile. (5) Teaching and non-teaching personnel differ significantly in personality. (6) Personality is significantly correlated with professional position. (7) No meaningful relationship exists between personality and years of experience. (8) No meaningful relationship exists between the personalities of educators and the personalities of the individuals responsible for hiring them. (9) The personalities of educators who strongly perceive that the Lord recruited them differ significantly from the personalities of individuals recruited by men. (10) No meaningful relationship exists between the personalities of teachers and the grade levels to which they are assigned. (11) No meaningful relationship exists between the personalities of educators and the size of school to which they are assigned. (12) The personalities of educators expressing a preference for one-teacher schools differ significantly from the personalities of educators preferring larger schools. (13) Demands for personnel in one-teacher schools clearly exceed the supply of teachers preferring such placement. (14) Personality is significantly correlated with levels of perceived competence. (15) No meaningful relationship exists between the personalities of educators judged most competent and the personalities of the supervisors passing judgment. (16) The personalities of female educators are significantly correlated with their opportunities for advancement. (17) No meaningful relationship exists between the personalities of educators selected for advancement and the personalities of administrators making the selections. (18) The personalities of highly stable educators differ significantly from the personalities of highly mobile educators

Episiotomy and Obstetric Trauma in Nevada: Evidence from Linked Hospital Discharge and Birth Data

Based on the perception that episiotomy prevents obstetric trauma, the procedure is liberally performed in U.S. Hospitals. Using linked Nevada Birth Registry and Nevada Impatient Hospital Discharges (2000 to 2005), we applied descriptive analyses and logistic regression to examine the status of Nevada episiotomy practice and its impact on birth trauma for mothers. Of 106,461 vaginal live births, 26,383 (24.8%) episiotomies were conducted. Obstetric trauma rate declined from 5.2% of vaginal deliveries in 2000 to 4.4% in 2005. After statistically controlling for the effect of other risk factors, zero parity, episiotomy, other instrument assisted deliveries, non-MDs as birth attendants, rural hospitals, urban county residences, and non-teaching hospitals are associated with an elevated risk obstetric trauma. We conclude that Nevada is on par with the year over year decline in national episiotomy rates

A method for determining average iron content of ferritin by measuring its optical dispersion

© 2019 American Chemical Society. We report a method where the refractive index increments of an iron storage protein, ferritin, and apoferritin (ferritin minus iron) were measured over the wavelength range of 450-678 nm to determine the average iron content of the protein. The protein used in this study had ∼3375 iron atoms per molecule. The measurement of optical dispersion over the broad wavelength range was enabled by the use of mesoporous leaky waveguides (LWs) made of chitosan. We present a facile approach for fabricating mesoporous chitosan waveguides for improving the measurement sensitivity of macromolecules such as ferritin. Mesoporous materials allow macromolecules to diffuse into the waveguide, maximizing their interaction with the optical mode and thus increasing sensitivity by a factor of ∼9 in comparison to nonporous waveguides. The sensitivity was further improved and selectivity toward ferritin was achieved by the incorporation of antibodies in the waveguide. The method presented in this work is a significant advance over the state of the art method, the enzyme linked immunosorbent assay (ELISA) used in clinics, because it allows determining the average content of ferritin in a single step. The average iron content of ferritin is an important marker for conditions such as injury, inflammation, and infection. Thus, the approach presented here of measuring optical dispersion to determine the average iron content of ferritin has a significant potential to improve the point of care analysis of the protein for disease diagnosis and screening

Biosensor for determining average iron content of ferritin by measuring its optical dispersion

© 2020 SPIE. Average iron content of ferritin has a potential to serve as a biomarker for early identification of high-risk trauma patients at point-of-care (PoC). Appropriate therapies can then be administered to reduce morbidity and mortality. Currently, protein and iron levels are measured separately using enzyme-linked immunosorbent assay (ELISA) and UV or atomic absorption spectroscopy (AAS) respectively, but the use of two completely different methods adds to the complexity and analysis time of the combined measurement. As a result, these methods are unsuitable for PoC analysis. To address this gap, we report a biosensor for measuring the average iron content of ferritin in a single step. The biosensor was based on a dye-doped leaky waveguide (LW), which operates in the entire visible wavelength range, and hence allowed the measurement of differences in the optical dispersion of ferritin and apoferritin to determine the average iron content of the protein. The LW biosensor comprised a 1.54 micron thick mesoporous chitosan slab waveguide with immobilized antibodies against ferritin/apoferritin to measure the optical dispersion of 110 nM protein. Based on the baseline noise, the limit of detection for this method is ∼700 pM for ferritin/apoferritin. The biosensor has a significant potential for PoC measurement of the average iron content of serum ferritin and, in future, the total protein cencentration

960-86 Implications of Alternative Classifications of Sudden Cardiac Death: A Prospective Analysis of 109 Deaths in Defibrillator Trials

In order to explore the implications of using varied definitions of sudden cardiac death (SCD), a classification (CL) committee (3 cardiologists) prospectively evaluated 109 deaths over a period of 19 months in patients with an implantable cardioverter defibriliator (ICD). The basis for CL was the CAST approach with additional assessments of the consequences of considering autopsy and ICD interrogation information. Concordance and/or discordance between committee members was recorded.ResultsOf the 834 patients followed for 19 months, there were 109 deaths: 17 were classified SCD, 51 non-SCD. and 40 non-cardiac. Of the deaths classified as SCD, 10/17 were unwitnessed as compared to 6/51 non-SCD and 3/40 non-cardiac deaths; p < 0.001. ICD detections occurred in 5/17 SCD <1 hour, 7/17 SCD <6 hours; therefore, 10/17 SCD had no ICD detection or information available. There was committee discordance in 5/17 SCD compared to 18/51 non-SCD and 16/40 non-cardiac. SCD rates as high as 3.6% (30/834) can be estimated if all SCD cases Cl by ≥1 member was counted as SCD. Likewise. a SCD rate as low as 0.8% (7/834) is possible if SCD is limited to witnessed SCD ≤1 hour; (a 4-fold difference). Autopsy information was available in 29/109 deaths. In 7 cases, autopsy findings resulted in changing a “SCD” CL (5 witnessed; 2 unwitnessed) to either non-SCD or non-cardiac [ruptured abdominal (N=21 or thoracic aortic (N=1) aneurysm, acute MI (N=1), cerebral infarction (N=1). pulmonary embolism (N=2)]. Thus, had autopsy information been unavailable or not considered, the SCD rate would have increased to 24/834 12.9%). ICD interrogation was unavailable in 51/109 (47%), most commonly due to being buried with the patient or programmed off prior to death.ConclusionA 4-fold spectrum of SCD rates is possible to report from the identical data-set. ICD interrogation has significant limitations for use in death CL, in contrast to its utility in clinical management. Autopsy results clarify cause-specific mortality in deaths that are temporally quite “sudden.” Total mortality is the most objective primary end point

Selection of Psyllid-Resistant Forage Varieties from an Inter-Specific Breeding Program of \u3cem\u3eLeucaena leucocephala\u3c/em\u3e with \u3cem\u3eL. pallida\u3c/em\u3e

Leucaena (Leucaena leucocephala) pastures for beef cattle production are productive and sustainable; however, susceptibility to the psyllid insect (Heteropsylla cubana) has limited expansion of current commercial cultivars into more humid areas (\u3e 800 mm/yr) (Shelton and Dalzell 2007). Psyllids can also cause intermittent damage in lower rainfall regions during humid periods. The psyllid, which arrived in Australia in 1986, is a leaf-sucking insect specific to the Leucaena genus, feeding on the growing tips of susceptible cultivars (Bray 1994). Psyllid damage can reduce production by as much as 50-70% in humid regions and 20-50% in subhumid environments (Bray 1994; Mullen and Shelton 2003). Work on psyllid resistance in the Leucaena genus through the 1990s showed that several Leucaena species, including the tetraploid L. pallida, had good levels of resistance (Mullen et al. 2003). A breeding program to develop psyllid-resistant varieties began in 2002 at The University of Queensland (UQ) based on the F1 inter-specific hybrids between L. leucocephala and L. pallida (known as ‘KX2’), developed at the University of Hawaii (Brewbaker 2008). Between 2002 and 2005, UQ initiated a program of recurrent selection in an attempt to produce stable outcrossed KX2-derived lines but inbreeding depression for yield and poor forage quality led to a change in the breeding strategy, and a backcrossing program was implemented between 2005 and 2008. Two cycles of backcrossing to elite L. leucocephala ssp. glabrata material were completed followed by 2 cycles of progeny testing and selection for self-compatibility to achieve stability and uniformity (2009 - 2012). Forty elite psyllid-resistant lines were then evaluated to identify the most suitable lines for release to industry. This paper describes the results of these trials

A new liver perfusion and preservation system for transplantation Research in large animals

A kidney perfusion machine, model MOX-100 (Waters Instruments, Ltd, Rochester, MN) was modified to allow continuous perfusion of the portal vein and pulsatile perfusion of the hepatic artery of the liver. Additional apparatus consists of a cooling system, a membrane oxygenator, a filter for foreign bodies, and bubble traps. This system not only allows hypothermic perfusion preservation of the liver graft, but furthermore enables investigation of ex vivo simulation of various circulatory circumstances in which physiological perfusion of the liver is studied. We have used this system to evaluate the viability of liver allografts preserved by cold storage. The liver was placed on the perfusion system and perfused with blood with a hematocrit of approximately 20% and maintained at 37°C for 3 h. The flows of the hepatic artery and portal vein were adjusted to 0.33 mL and 0.67 mL/g of liver tissue, respectively. Parameters of viability consisted of hourly bile output, oxygen consumption, liver enzymes, electrolytes, vascular resistance, and liver histology. This method of liver assessment in large animals will allow the objective evaluation of organ viability for transplantation and thereby improve the outcome of organ transplantation. Furthermore, this pump enables investigation into the pathophysiology of liver ischemia and preservation. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted